Payment & Shipping Terms:
|Quantity:||4 Nmol||Turnaround Time:||10~20 Days|
SgRNAs Crispr Cas Gene Editing,
Lyophilized Powder Crispr Cas Gene Editing,
4 nmol Crispr Cas Gene Editing
CRISPR/Cas9 technology is a powerful tool for creating gene knock-ins and knock-outs. Using the ribonucleoprotein (RNP) system for delivering CRISPR/Cas9 has many advantages over the traditional plasmids or virus based delivery methods.
The CRISPR-Cas9 system is a prokaryotic immune system driven by RNA that triggers resistance to foreign genetic elements and provides a form of acquired immunity. sgRNA serves as a guide to recognize and combine target with DNAs, allowing activated Cas9 nuclease to attach, cleave, and modify the PAM downstream target DNA. CRISPR-based genome editing technology has made it easier and faster than ever to alter specific DNA sequence in the genome or to perform genome-wide functional screening tests to identify genes involved in a particular phenotype. CRISPR-Cas9 is considered as the most promising tool in gene modification.
Offer modified sgRNAs for better stability and editing efficiency
RNase-free HPLC guaranteeing more than 90% purity
97-103nt length range, allowing for greater flexibility in design
ESI-MS guaranteeing mass variation less than 1‰
4 nmol guaranteed delivery quantity
*Deliver in as short as 8 business days.
|CRISPR sgRNA||97 to 103 nt||4 nmol|
|Modified CRISPR sgRNA (2'-O-methyl and phosphorothioate modifications at the first three 5' and 3' terminal RNA residues)||97 to 103 nt||4 nmol|