Aquaporins AqpZ Bacterial Nodulin Like Intrinsic Protein Water Channel Protein

We offer Aquaporin-Z, AqpZ, major intrinsic protein, cell-free protein isolated by nanodiscs.

Our Cell-free protein has been Function verificated.

Advantage of E.Coli system

1. High protein yield
2. Simple cultivation and fast cell growth and lysate preparation
3. Cost-efficient
4. Easy genetic engineering
5. Well-established

Introduction

Aquaporin Z is considered as channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.

Molecular water channels (aquaporins) allow living cells to adapt to osmotic variations by rapid and specific diffusion of water molecules. Aquaporins are present in animals, plants, algae, fungi and bacteria. Aquaporin Z (AqpZ), was the first water channel to be recognized in prokaryotes.

Stucture

The 8 A projection map of the AqpZ tetramer in frozen hydrated samples is similar to that of AQP1, consistent with the high sequence homology between these proteins.

Target sequence

MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISG

GHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFAS

NGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPV

TNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRD