MiRNA Inhibitors MiRNA Mimics MiRNA Agomir Antagomir Mirna Negative Control MiRNA Synthesis

CELLFREE offers a wide range of high quality miRNA synthesis services, including miRNA inhibitors/mimics, miRNA agomirs/antagomirs and miRNA negative controls, etc. to support your miRNA functional research. 

miRNA inhibitors

With the Anti-miR miRNA inhibitors, you can:

• Control specific miRNA activity
• Tightly regulate miRNA cellular levels
• Achieve optimal delivery efficiency with minimal cytotoxicity

Use of the miRNA inhibitors will enable miRNA functional analysis for down-regulation of miRNA activity. Specific experimental designs include:

• miRNA target site identification and validation
• Screening for miRNAs that regulate the expression of a gene
• Screening for miRNAs that affect a cellular process

miRNA mimics

miRNA are designed to directly enter the miRNA processing pathway and, after processing, are treated identically to endogenous miRNA within the cell. You can:

• Control specific miRNA activity
• Tightly regulate miRNA cellular levels
• Achieve optimal delivery efficiency with minimal cytotoxicity

MiRNA enables up-regulation of miRNA activity for miRNA functional analysis. Specific experimental designs include:

• miRNA target site identification and validation
• Screening for miRNAs that regulate the expression of a gene
• Screening for miRNAs that affect a cellular process

miRNA agomir & antagomir

The Chemically-modified Construction of Antagomir and Agomir
Antogimir: 3’ terminal was modified by cholesterol, there are two thiols modification in the 5’ terminal, four thiols modification in the 3’ terminal, and the whole strand is modified by 2’-OMe.
Agomir: in the antisense strand, 3’ terminal was modified by cholesterol, there are two thiols modification in the 5’ terminal, four thiols modification in the 3’ terminal, and the whole strand is modified by OMe.

miRNA negative control