Product Details:
Payment & Shipping Terms:
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Service: | Recombinant Antibodies | Fragment Type: | ScFv/Fab |
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Composition: | VH, VL(CH1, CL) | M.W.: | 30/50 |
Retention Times: | Very Short/short | Method: | Enzymatic/recombinant Methods |
High Light: | Antigen Binding Fragment Antibody Discovery,Single Chain Fragment Antibody Discovery |
Formats of Recombinant Antibodies
There are many formats of recombinant antibodies, such as scFv, Fab fragment, bispecific antibody (BsAb), and single domain antibody (sdAb). Each of them has a slightly different potential in applications and various fields of research.
scFv Construction
These antibody fragments are commonly generated by phage display technology, which give several advantages in gaining new antibodies or human antibodies. Basically, there are two following methods to generate a scFv fragment for a specific antigen:
Fab Construction
Three different methods are used for generating the Fab fragments:
Service Specification
With rich experience in the field of recombinant antibody, CELLFREE has established a solid platform for scFv or Fab construction that can offer one-stop solution for antibody engineering and accelerate your research.
Fragment Type |
scFv |
Fab |
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Composition |
VH, VL |
VH, VL,CH1, CL |
M.W. (kDa) |
30 |
50 |
Blood clearance |
Very rapid |
Rapid |
Tumor penetration |
Great |
Good |
Retention times |
Very short |
Short |
Affinity |
Reduced |
Better than scFv |
Stability |
Unstable over longer periods |
High stability in long-term storage |
Production |
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