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|Appearance:||Lyophilized Or Liquid||MW:||52kDa|
|Tool:||Nanodisc||CFPS:||E. Coli Extract|
GPCR Cell Free Protein,
52 kDa MW Cell Free Protein,
Adrb1r Cell Free Protein
We supply ADRB1; adrenergic, beta-1-, receptor; beta-1 adrenergic receptor; ADR B1; ADRB 1; ADRB1_HUMAN; ADRB1R; Adrenergic beta 1 receptor; B1AR; Beta 1 adrenoceptor; Beta 1 adrenoreceptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR; RHR.
Our Cell-free protein has been Function verificated.
Beta-adrenergic receptors (Beta-1 adrenoreceptor) mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Subcellular location cell membrane; Multi-pass membrane protein. Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. Belongs to the G-protein coupled receptor 1 family.
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
ADRB1 involved in several pathways and played different roles in them. ADRB1 has several biochemical functions, for example, PDZ domain binding, Ras guanyl-nucleotide exchange factor activity, alpha-2A adrenergic receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADRB1 itself.
Interacts with GOPC, MAGI3 and DLG4.
Cell membrane; Multi-pass membrane protein. Note:Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression.
Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
Belongs to the G-protein coupled receptor 1 family.
Adrenergic receptor subfamily. ADRB1 sub-subfamily.
Advantage of E.Coli system
For Research Use Only. Not for use in diagnostic procedures