Product Details:
Payment & Shipping Terms:
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Starting Raw Material: | 10 Kb Or Larger Genomic Clone | Preferably: | 10 µg Of DNA |
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Electronic Data: | Publication-ready Photographs And Diagrams | Applications-1: | Cellular Chromosome FISH |
Applications-2: | Tissue Chromosome FISH | Applications-3: | RNA-FISH |
High Light: | 10µg DNA Fluorescence In Situ Hybridization,10kb Clone Fluorescence In Situ Hybridization |
Introduction
Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors. This technique is useful for identifying chromosomal abnormalities, gene mapping, characterizing somatic cell hybrids, checking amplified genes and studying the mechanism of rearrangements. RNA FISH is used to measure and localize mRNAs and other transcripts within tissue sections or whole mounts.
We are dedicated to provide the most comprehensive list of histology service and custom design services to academia as well as industrial researchers and clinical institutes all around the world. We offer Fluorescence in situhybridization (FISH) service range from standardized testing of validated assays to custom development of new assays. Drawing on many years of experiences and in-depth knowledge, we guarantee the speed, quality and cost of our service. CELLFREE is your first and most reliable choice in histology.
We offers a variety of FISH services to further analyze your clones. With our FISH services, we will provide you with a written report that includes a brief description of methods used, a brief description of results, and final conclusion of the tests. If appropriate, we'll also provide photographic documentation, along with the number of cells analyzed. Simply supply a 10 kb or larger genomic clone, preferably cosmid size or larger, and at least 10 µg of DNA.
DATA FOR FISH SERVICES
Detailed descriptions of methods, results and references.
Publication-ready photographs with figure legends.
Publication-ready diagrams (for gene mapping).
The following picture examples are provided.
Usage
• to identify complex chromosome aberrations
• to identify small partial trisomies
• to identify small marker chromosomes
• to refine chromosome breakpoints
• to detect small emerging abnormal clones
Services
• duplications and deletions >40KB
• low level mosaicism
• unbalanced translocations
• cryptic chromosome aberrations